Gamma Secretase Inhibitors: Potentiating BCMA-Targeted Therapies

Time: 2:30 pm
day: Day Two


  • Synergistic mechanism of action for gamma secretase inhibition on BCMA
    applies to all BCMA-targeted therapy modalities
  • Sharing an open development approach by partnering across all BCMA modalities and also broadly within each modality
  • GSI + BCMA combination synergy and potentiation as an example of translational medicine and precision medicine from proof-of-concept to validation with safety and efficacy evidence from clinical trials